The MBL2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to mannan-binding lectin, Mannose Binding Lectin, MBL-C, MBL2, and MBP-C. This antibody recognizes Human antigen. The MBL2 Antibody has been validated for the following applications: Western Blot.
Description
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.Ezekowitz R.A.B., J. Exp. Med. 167:1034-1046(1988).Sastry K., J. Exp. Med. 170:1175-1189(1989).Taylor M.E., Biochem. J. 262:763-771(1989)